Golgi localization of SARS-CoV-2 spike protein and interaction with furin in cerebral COVID-19 microangiopathy: a clue to the central nervous system involvement?

In a neuropathological series of 20 COVID-19 cases, we analyzed six cases (three biopsies and three autopsies) with multiple foci predominantly affecting the white matter as shown by MRI.The cases presented with microhemorrhages evocative of small artery diseases.This COVID-19 associated cerebral microangiopathy (CCM) was characterized by perivascu

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